Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes.

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作者： Stephan,Culemann ^[1] ; Katharina,Knab ^[1] ; Maximilien,Euler ^[1] ; Anja,Wegner ^[1] ; Hilal,Garibagaoglu ^[1] ; Jochen,Ackermann ^[1] ; Kim,Fischer ^[1] ; Deborah,Kienhöfer ^[1] ; Georgiana,Crainiciuc ^[2] ; Jonas,Hahn ^[1] ; Anika,Grüneboom ^[1] ; Falk,Nimmerjahn ^[3] ; Stefan,Uderhardt ^[1] ; Andrés,Hidalgo ^[4] ; Georg,Schett ^[1] ; Markus H,Hoffmann ^[5] ; Gerhard,Krönke ^[1]

作者单位： Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen , Erlangen, Germany.;Deutsches Zentrum für Immuntherapie, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen , Erlangen, Germany. ^[1] Area of Cell and Developmental Biology, Centro Nacional de Investigaciones Cardiovasculares Carlos III , Madrid, Spain. ^[2] Institute of Genetics at the Department of Biology, Friedrich-Alexander University Erlangen-Nürnberg , Erlangen, Germany. ^[3] Area of Cell and Developmental Biology, Centro Nacional de Investigaciones Cardiovasculares Carlos III , Madrid, Spain.;Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine , New Haven, CT, USA. ^[4] Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen , Erlangen, Germany.;Deutsches Zentrum für Immuntherapie, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen , Erlangen, Germany.;Department of Dermatology, Allergy and Venerology, University of Lübeck , Lübeck, Germany. ^[5]

主题词人类(Humans);脂质体(Liposomes);氯膦酸(Clodronic Acid);中性白细胞(Neutrophils);炎症(Inflammation);消炎药(Anti-Inflammatory Agents)

DOI 10.1084/jem.20220525

PMID 36976180

发布时间 2024-09-23

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