Immunochemical and LC-MS/MS Detection of Protein Adduction Resulting from Metabolic Activation of Columbin In Vitro and In Vivo.

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第一作者： Chutian,Wu

第一单位： State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang 550004, Guizhou, PR China.

作者： Chutian,Wu ^[1] ; Jie,Pan ^[2] ; Bowen,Gong ^[1] ; Yufen,Liao ^[2] ; Ying,Zou ^[1] ; Yang,Wang ^[2] ; Guangyun,Ran ^[1] ; Xin,Wang ^[2] ; Mengyue,Zhou ^[1] ; Ting,Liu ^[2] ; Ying,Peng ^[1] ; Weiwei,Li ^[2] ; Jiang,Zheng ^[1]

作者单位： State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang 550004, Guizhou, PR China. ^[1] School of Pharmacy, Guizhou Medical University, Guiyang 550004, Guizhou, PR China. ^[2] Wuya of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, PR China. ^[3] Key Laboratory of Environmental Pollution, Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550025, PR China. ^[4]

主题词色谱法, 液相(Chromatography, Liquid);串联质谱法(Tandem Mass Spectrometry);赖氨酸(Lysine);二萜类(Diterpenes);蛋白质类(Proteins)

DOI 10.1021/acs.chemrestox.3c00006

PMID 36976707

发布时间 2023-05-08

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