Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells.

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作者： Mina,Yeom ^[1] ; Jin-Kyung,Hong ^[1] ; Joo-Ho,Shin ^[1] ; Yunjong,Lee ^[1] ; Frederick Peter,Guengerich ^[2] ; Jeong-Yun,Choi ^[1]

作者单位： Department of Pharmacology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea. ^[1] Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA. ^[2]

关键词 DNA polymerase η UV XPV cisplatin germline variant translesion DNA synthesis

主题词人类(Humans);顺铂(Cisplatin);紫外线(Ultraviolet Rays);指导DNA的DNA聚合酶(DNA-Directed DNA Polymerase);DNA修复(DNA Repair);DNA(DNA);着色性干皮病(Xeroderma Pigmentosum);DNA损伤(DNA Damage);生殖细胞(Germ Cells)

DOI 10.3390/ijms24065198

PMID 36982269

发布时间 2024-05-10

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International journal of molecular sciences

2023年24卷6期

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Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells.

International journal of molecular sciences

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International journal of molecular sciences

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Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells.

International journal of molecular sciences

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International journal of molecular sciences

相关期刊

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