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首页> eLife> Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.

Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.

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作者： Danielle B,Buglak ^[1] ; Pauline,Bougaran ^[2] ; Molly R,Kulikauskas ^[1] ; Ziqing,Liu ^[2] ; Elizabeth,Monaghan-Benson ^[3] ; Ariel L,Gold ^[2] ; Allison P,Marvin ^[2] ; Andrew,Burciu ^[2] ; Natalie T,Tanke ^[1] ; Morgan,Oatley ^[2] ; Shea N,Ricketts ^[4] ; Karina,Kinghorn ^[1] ; Bryan N,Johnson ^[2] ; Celia E,Shiau ^[2] ; Stephen,Rogers ^[2] ; Christophe,Guilluy ^[3] ; Victoria L,Bautch ^[1]

作者单位： Curriculum in Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, United States. ^[1] Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, United States. ^[2] Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, United States. ^[3] Department of Pathology, The University of North Carolina at Chapel Hill, Chapel Hill, United States. ^[4] McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, United States. ^[5]

关键词 GEF-H1 Nesprin-1 Rho SUN1 adherens junctions angiogenesis blood vessels cell biology contractility endothelial cell endothelial cells microtubules mouse nuclear LINC complex zebrafish

主题词动物(Animals);小鼠(Mice);微管相关蛋白质类(Microtubule-Associated Proteins);内皮细胞(Endothelial Cells);斑马鱼(Zebrafish);核蛋白质类(Nuclear Proteins);微管(Microtubules);细胞连接(Intercellular Junctions)

DOI 10.7554/eLife.83652

PMID 36989130

发布时间 2023-06-17

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