Hepatitis C virus fitness can influence the extent of infection-mediated epigenetic modifications in the host cells.

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作者： Carlos,García-Crespo ^[1] ; Irene,Francisco-Recuero ^[2] ; Isabel,Gallego ^[3] ; Marina,Camblor-Murube ^[1] ; María Eugenia,Soria ^[2] ; Ana,López-López ^[3] ; Ana Isabel,de Ávila ^[1] ; Antonio,Madejón ^[2] ; Javier,García-Samaniego ^[4] ; Esteban,Domingo ^[3] ; Aurora,Sánchez-Pacheco ^[1] ; Celia,Perales ^[2]

作者单位： Department of Interactions with the Environment, Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Consejo Superior de Investigaciones Científicas (CSIC), Campus de Cantoblanco, Madrid, Spain. ^[1] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain. ^[2] Department de Biochemistry, UAM, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid, Spain. ^[3] Department of Clinical Microbiology, IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain. ^[4] Hepatology Unit Hospital Universitario La Paz/Carlos III, Instituto de Investigación Sanitaria "La Paz", Madrid, Spain. ^[5] Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain. ^[6]

关键词 aurora kinase B hepatitis C virus hepatocellular carcinoma histone modification viral fitness viral quasispecies virus-host interaction

主题词人类(Humans);肝炎病毒属(Hepacivirus);病毒复制(Virus Replication);丙型肝炎(Hepatitis C);癌, 肝细胞(Carcinoma, Hepatocellular);后成说, 遗传(Epigenesis, Genetic)

DOI 10.3389/fcimb.2023.1057082

PMID 36992689

发布时间 2023-04-07

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