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First-in-human clinical trial of the NKT cell-stimulatory glycolipid OCH in multiple sclerosis.

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第一作者： Wakiro,Sato

第一单位： Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan.

作者： Wakiro,Sato ^[1] ; Daisuke,Noto ^[2] ; Manabu,Araki ^[3] ; Tomoko,Okamoto ^[4] ; Youwei,Lin ^[4] ; Hiromi,Yamaguchi ^[1] ; Ryoko,Kadowaki-Saga ^[1] ; Atsuko,Kimura ^[1] ; Yukio,Kimura ^[5] ; Noriko,Sato ^[5] ; Takami,Ishizuka ^[6] ; Harumasa,Nakamura ^[6] ; Sachiko,Miyake ^[7] ; Takashi,Yamamura ^[8]

作者单位： Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan. ^[1] Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan.;Department of Immunology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan. ^[2] Multiple Sclerosis Center, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan. ^[3] Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan. ^[4] Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan. ^[5] Translational Medical Center, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan. ^[6] Department of Immunology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan. ^[7] Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8502, Japan.;Multiple Sclerosis Center, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan. ^[8]

关键词 OCH Treg cells clinical trial iNKT cells multiple sclerosis

DOI 10.1177/17562864231162153

PMID 36993937

发布时间 2023-03-31

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