Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters.

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作者： Yu,Cong ^[1] ; Eric M,Mucker ^[2] ; Donna L,Perry ^[1] ; Saurabh,Dixit ^[1] ; Erin,Kollins ^[1] ; Russ,Byrum ^[1] ; Louis,Huzella ^[1] ; Robert,Kim ^[2] ; Mathew,Josleyn ^[2] ; Steven,Kwilas ^[2] ; Christopher,Stefan ^[2] ; Charles J,Shoemaker ^[2] ; Jeff,Koehler ^[2] ; Susan,Coyne ^[2] ; Korey,Delp ^[2] ; Janie,Liang ^[1] ; David,Drawbaugh ^[1] ; Amanda,Hischak ^[1] ; Randy,Hart ^[1] ; Elena,Postnikova ^[1] ; Nick,Vaughan ^[1] ; Jason,Asher ^[3] ; Marisa,St Claire ^[1] ; Jarod,Hanson ^[2] ; Connie,Schmaljohn ^[1] ; Ann E,Eakin ^[4] ; Jay W,Hooper ^[2] ; Michael R,Holbrook ^[5]

作者单位： Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, MD, 21702, USA. ^[1] United States Army Medical Research Institute of Infectious Diseases, Ft. Detrick, Frederick, MD, 21702, USA. ^[2] Leidos Supporting Department of Health and Human Services, Biomedical Advanced Research and Development Authority, Washington, DC, 20024, USA. ^[3] Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20892, USA. ^[4] Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Ft. Detrick, Frederick, MD, 21702, USA. Electronic address: michael.holbrook@nih.gov. ^[5]

关键词 Animal model Antibody cocktail COVID-19 Monoclonal antibody SARS-CoV-2 Therapeutic antibody