Buyang huanwu decoction inhibits diabetes-accelerated atherosclerosis via reduction of AMPK-Drp1-mitochondrial fission axis.

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作者： Wanyu,Tong ^[1] ; Ling,Leng ^[2] ; Yucheng,Wang ^[1] ; Jingwen,Guo ^[1] ; Felix Boahen,Owusu ^[1] ; Yue,Zhang ^[1] ; Fang,Wang ^[1] ; Ruiqiao,Li ^[2] ; Yuhong,Li ^[2] ; Yanxu,Chang ^[3] ; Yuefei,Wang ^[4] ; Qilong,Wang ^[5]

作者单位： Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. ^[1] Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin, 301617, China. ^[2] Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China. ^[3] Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China. Electronic address: wangyf0622@tjutcm.edu.cn. ^[4] Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; State Key Laboratory of Component-Based Chinese Medicine, Ministry of Education, Tianjin, 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China. Electronic address: wangqilong_00@tjutcm.edu.cn. ^[5]

关键词 AMPK Astragaloside IV (PubChem CID:13943297)Atherosclerosis Buyang huanwu decoction Calycosin-7-glucoside (PubChem CID:71571502)Drp1 Endothelial dysfunction Ferulic acid (PubChem CID:1548883)Mitochondrial dynamics Ononin (PubChem CID:442813)Paeoniflorin (PubChem CID:442534)