Development of a MET-targeted single-chain antibody fragment as an anti-oncogene targeted therapy for breast cancer.

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第一作者： Rana,Vafaei

第一单位： Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.;Recombinant Proteins Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.

作者： Rana,Vafaei ^[1] ; Zohreh,Khaki ^[2] ; Malihe,Salehi ^[3] ; Neda,Jalili ^[3] ; Mohammad Reza,Esmailinejad ^[4] ; Ahad,Muhammadnajad ^[5] ; Seyed Mahdi,Nassiri ^[6] ; Alireza,Vajhi ^[7] ; Shima Moradi,Kalbolandi ^[3] ; Roya,Mirzaei ^[3] ; Leila,Farahmand ^[8]

作者单位： Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.;Recombinant Proteins Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran. ^[1] Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran. zkhaki@ut.ac.ir. ^[2] Recombinant Proteins Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran. ^[3] Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.;Shahid Bahonar University of Kerman, Department of Clinical Sciences, Faculty of Veterinary Medicine, Kerman, Iran. ^[4] Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran. ^[5] Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran. ^[6] Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran. ^[7] Recombinant Proteins Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran. laylafarahmand@gmail.com. ^[8]

关键词 Antibody fragment Breast Cancer MET Receptor tyrosine kinase Recombinant scFv