Sciatic nerve fractional anisotropy and neurofilament light chain protein are related to sensorimotor deficit of the upper and lower limbs in patients with type 2 diabetes.

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作者： Zoltan,Kender ^[1] ; Johann M E,Jende ^[2] ; Felix T,Kurz ^[3] ; Dimitrios,Tsilingiris ^[3] ; Lukas,Schimpfle ^[4] ; Alba,Sulaj ^[1] ; Ekaterina,von Rauchhaupt ^[2] ; Hannelore,Bartl ^[1] ; Christoph,Mooshage ^[1] ; Jens,Göpfert ^[2] ; Peter,Nawroth ^[1] ; Stephan,Herzig ^[2] ; Julia,Szendroedi ^[1] ; Martin,Bendszus ^[3] ; Stefan,Kopf ^[5]

作者单位： Department of Endocrinology, Diabetology and Clinical Chemistry (Internal Medicine 1), Heidelberg University Hospital, Heidelberg, Germany. ^[1] German Center of Diabetes Research [Deutsches Zentrum für Diabetesforschung (DZD)], München, Germany. ^[2] Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany. ^[3] Department of Radiology, German Cancer Research Center, Heidelberg, Germany. ^[4] NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany. ^[5] Joint-IDC Institute for Diabetes and Cancer, Heidelberg University, Heidelberg, Germany. ^[6] Joint-IDC Institute for Diabetes and Cancer, Helmholtz-Zentrum Munich, Munich, Germany. ^[7]

关键词 diabetic neuropathy diffusion tensor imaging fractional anisotropy magnetic resonance neurography neurofilament light chain protein quantitative sensory testing

主题词人类(Humans);糖尿病, 2型(Diabetes Mellitus, Type 2);各向异性(Anisotropy);中间丝(Intermediate Filaments);坐骨神经(Sciatic Nerve);糖尿病神经病变(Diabetic Neuropathies);下肢(Lower Extremity)

DOI 10.3389/fendo.2023.1046690

PMID 37008917

发布时间 2023-04-10

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