Tomentosin suppressed M1 polarization via increasing MERTK activation mediated by regulation of GAS6.

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作者： Yu-Xi,Di ^[1] ; Yu-Jie,Bao ^[2] ; Zhi-Qi,Zhu ^[3] ; Shan-Liang,Sun ^[4] ; Feng-Xiang,Tian ^[5] ; Fu-Rong,Wang ^[6] ; Ge,Yu ^[7] ; Ming-Fei,Zhang ^[8] ; Jing,Han ^[9] ; Ling-Ling,Zhou ^[10]

作者单位： School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: diyuxi0514@163.com. ^[1] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: aouie0226@163.com. ^[2] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: zhuzhiqidyx@126.com. ^[3] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: ssun@njucm.edu.cn. ^[4] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: tfx311henan@163.com. ^[5] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: wangfurong12@126.com. ^[6] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: 2380189936@qq.com. ^[7] Department of Pharmacy, Affiliated Hospital of Yangzhou University, Yangzhou University, 45 Taizhou Road, 225003, Yangzhou, PR China. Electronic address: zmfei1135@163.com. ^[8] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: hanjing@njucm.edu.cn. ^[9] School of Pharmacy, Nanjing University of Chinese Medicine, NO.138 Xianlin Road, 210023, Nanjing, Jiangsu Province, PR China. Electronic address: zhoulingling@njucm.edu.cn. ^[10]

关键词 Collagen-induced arthritis GAS6 Inflammation MERTK Macrophages Traditional Chinese medicine

主题词小鼠(Mice);动物(Animals);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);炎症(Inflammation);消炎药(Anti-Inflammatory Agents);关节炎, 类风湿(Arthritis, Rheumatoid);关节炎, 实验性(Arthritis, Experimental)

DOI 10.1016/j.jep.2023.116429

PMID 37011736

发布时间 2023-06-05

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准确一般字义偏差语意偏离译文作用小提交