Structural and molecular insights into tacrine-benzofuran hybrid induced inhibition of amyloid-β peptide aggregation and BACE1 activity.
第一作者:
Rajdeep,Kaur
第一单位:
Department of Chemistry, Faculty of Basic and Applied Sciences, Sri Guru Granth Sahib World University, Fatehgarh Sahib, Punjab, India.
作者:
主题词
人类(Humans);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);他克林(Tacrine);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);配体(Ligands);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);阿尔茨海默病(Alzheimer Disease);分子动力学模拟(Molecular Dynamics Simulation);苯呋喃类(Benzofurans);肽碎片(Peptide Fragments)
DOI
10.1080/07391102.2023.2191722
PMID
37013977
发布时间
2023-11-27
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Journal of biomolecular structure & dynamics
13211-13227页
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