The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts.

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作者： Huadie,Liu ^[1] ; Lukai,Zhai ^[2] ; Ye,Liu ^[1] ; Di,Lu ^[1] ; Alexandra,Vander Ark ^[2] ; Tao,Yang ^[1] ; Connie M,Krawczyk ^[2]

作者单位： Laboratory of Skeletal Biology, Department of Cell Biology, Van Andel Institute, 333 Bostwick Ave NE, Grand Rapids, MI 49503, USA. ^[1] Department of Metabolism and Nutritional Programming, Van Andel Research Institute, Grand Rapids, MI 49503, USA. ^[2]

主题词动物(Animals);女(雌)性(Female);人类(Humans);男(雄)性(Male);小鼠(Mice);能量代谢(Energy Metabolism);后成说, 遗传(Epigenesis, Genetic);组蛋白脱甲基酶类(Histone Demethylases);破骨细胞(Osteoclasts);骨质疏松(Osteoporosis)

DOI 10.1126/sciadv.adg0731

PMID 37018401

发布时间 2023-05-27

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Science advances

2023年9卷14期

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The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts.

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The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts.

Science advances

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