T<sub>STEM</sub>-like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models.

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第一作者： Deborah,Meyran

第一单位： Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.

作者： Deborah,Meyran ^[1] ; Joe Jiang,Zhu ^[2] ; Jeanne,Butler ^[3] ; Daniela,Tantalo ^[1] ; Sean,MacDonald ^[3] ; Thu Ngoc,Nguyen ^[1] ; Minyu,Wang ^[1] ; Niko,Thio ^[1] ; Criselle,D'Souza ^[1] ; Vicky Mengfei,Qin ^[1] ; Clare,Slaney ^[3] ; Aaron,Harrison ^[1] ; Kevin,Sek ^[1] ; Pasquale,Petrone ^[3] ; Kevin,Thia ^[1] ; Lauren,Giuffrida ^[3] ; Andrew M,Scott ^[1] ; Rachael L,Terry ^[3] ; Ben,Tran ^[1] ; Jayesh,Desai ^[1] ; H Miles,Prince ^[3] ; Simon J,Harrison ^[1] ; Paul A,Beavis ^[1] ; Michael H,Kershaw ^[1] ; Ben,Solomon ^[4] ; Paul G,Ekert ^[5] ; Joseph A,Trapani ^[6] ; Phillip K,Darcy ^[7] ; Paul J,Neeson ^[3]

作者单位： Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia. ^[1] Université de Paris, Inserm, U976 HIPI Unit, Institut de Recherche Saint-Louis, Paris F-75010, France. ^[2] Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia. ^[3] Tumor Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, VIC 3084, Australia. ^[4] School of Cancer Medicine, La Trobe University, Melbourne, VIC 3086, Australia. ^[5] Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW 1466, Australia. ^[6] Division of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia. ^[7] School of Women's and Children's Health, UNSW Sydney, Sydney, NSW 1466, Australia. ^[8] Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia. ^[9] Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC 3052, Australia. ^[10]