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Polygenetic risk scores and phenotypic constellations of obsessive-compulsive disorder in clozapine-treated schizophrenia.

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第一作者： Carla Lou,Morgenroth

第一单位： Department of Psychiatry and Neurosciences, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany. carla-lou.morgenroth@charite.de.

作者： Carla Lou,Morgenroth ^[1] ; Philipp,Kleymann ^[2] ; Stephan,Ripke ^[2] ; Swapnil,Awasthi ^[2] ; Elias,Wagner ^[3] ; Tatiana,Oviedo-Salcedo ^[3] ; Cynthia,Okhuijsen-Pfeifer ^[4] ; Jurjen J,Luykx ^[5] ; Marte Z,van der Horst ^[6] ; Alkomiet,Hasan ^[7] ; Felix,Bermpohl ^[2] ; Stefan,Gutwinski ^[8] ; Stefanie,Schreiter ^[2]

作者单位： Department of Psychiatry and Neurosciences, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany. carla-lou.morgenroth@charite.de. ^[1] Department of Psychiatry and Neurosciences, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany. ^[2] Department of Psychiatry and Psychotherapy, University Hospital-LMU Munich, Munich, Germany. ^[3] Department of Psychiatry, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. ^[4] Department of Psychiatry, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.;Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands.;GGNet Mental Health, Warnsveld, The Netherlands. ^[5] Department of Psychiatry, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.;GGNet Mental Health, Warnsveld, The Netherlands. ^[6] Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Bezirkskrankenhaus Augsburg, Augsburg, Germany. ^[7] Department of Psychiatry and Neurosciences, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.;Department of Psychiatry, St. Hedwig-Krankenhaus, Charité-Universitätsmedizin, Berlin, Germany. ^[8]

关键词 Clozapine OCD PRS Schizophrenia

医学主题词人类(Humans);精神分裂症(Schizophrenia);氯氮平(Clozapine);精神分裂症心理学(Schizophrenic Psychology);强迫性障碍(Obsessive-Compulsive Disorder);共病现象(Comorbidity);表型(Phenotype)

DOI 10.1007/s00406-023-01593-y

PMID 37020043

发布时间 2024-01-15

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