Design, synthesis, antiviral and fungicidal activities of novel polycarpine simplified analogues.

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第一作者： Lili,Yan

第一单位： Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China.

作者： Lili,Yan ^[1] ; Yongyue,Gao ^[1] ; Taiqing,Li ^[1] ; Xiangyu,Wang ^[1] ; Rong,Xie ^[1] ; Yaxi,Liu ^[1] ; Yuxuan,Xie ^[1] ; Ziwen,Wang ^[2] ; Aidang,Lu ^[3] ; Qingmin,Wang ^[4]

作者单位： Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China. ^[1] Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China. Electronic address: hxxywzw@tjnu.edu.cn. ^[2] School of Chemical Engineering and Technology, Hebei University of Technology, Hebei Collaborative Innovation Center of Modern Marine Chemical Technology, Tianjin 300130, China. Electronic address: luaidang@hebut.edu.cn. ^[3] State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin 300071, China. Electronic address: wangqm@nankai.edu.cn. ^[4]

关键词 Action mechanism Anti-TMV activity Fungicidal activity Polycarpine simplified analogues

主题词抗病毒药(Antiviral Agents);杀真菌剂, 工业(Fungicides, Industrial);构效关系(Structure-Activity Relationship);烟草花叶病毒(Tobacco Mosaic Virus);真菌(Fungi);药物设计(Drug Design)

DOI 10.1016/j.bioorg.2023.106508

PMID 37023583

发布时间 2023-05-02

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