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High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias.

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第一作者： Alberto,Magi

第一单位： Department of Information Engineering, University of Florence, Florence, Italy. albertomagi@gmail.com.;Institute for Biomedical Technologies, National Research Council, Segrate, Milano, Italy. albertomagi@gmail.com.

作者： Alberto,Magi ^[1] ; Gianluca,Mattei ^[2] ; Alessandra,Mingrino ^[3] ; Chiara,Caprioli ^[4] ; Chiara,Ronchini ^[5] ; Gianmaria,Frigè ^[5] ; Roberto,Semeraro ^[3] ; Davide,Bolognini ^[3] ; Alessandro,Rambaldi ^[6] ; Anna,Candoni ^[7] ; Emanuela,Colombo ^[5] ; Luca,Mazzarella ^[5] ; Pier Giuseppe,Pelicci ^[8]

作者单位： Department of Information Engineering, University of Florence, Florence, Italy. albertomagi@gmail.com.;Institute for Biomedical Technologies, National Research Council, Segrate, Milano, Italy. albertomagi@gmail.com. ^[1] Department of Information Engineering, University of Florence, Florence, Italy. ^[2] Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy. ^[3] Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milano, Italy.;Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. ^[4] Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milano, Italy. ^[5] Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.;Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy. ^[6] Clinica Ematologica, Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy. ^[7] Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milano, Italy. piergiuseppe.pelicci@ieo.it.;Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. piergiuseppe.pelicci@ieo.it. ^[8]

医学主题词人类(Humans);CpG岛(CpG Islands);DNA(DNA);DNA甲基化(DNA Methylation);抗药性, 肿瘤(Drug Resistance, Neoplasm);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);纳米孔(Nanopores);转录因子(Transcription Factors);基因调控网络(Gene Regulatory Networks);抗肿瘤药(Antineoplastic Agents)

DOI 10.1038/s42003-023-04756-8

PMID 37031307

发布时间 2023-05-15

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Communications biology

2023年6卷1期

382页

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Communications biology

2023年6卷1期

382页

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High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias.

Communications biology

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High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias.

Communications biology

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Communications biology

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