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Distribution and Clinical Significance of HPV16 Variants in Head and Neck Squamous Cell Carcinomas: Data from a Portuguese Cohort and Systematic Review.

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第一作者： Daniela,Cochicho

第一单位： Research Department, NOVA Medical School University, Lisbon, Portugal, dcochicho@ipolisboa.min-saude.pt.;Virology Laboratory from Clinical Pathology Department, IPOLFG Portuguese Oncology Institute Francisco Gentil, Lisbon, Portugal, dcochicho@ipolisboa.min-saude.pt.

作者： Daniela,Cochicho ^[1] ; Alexandra,Nunes ^[2] ; Daniel,Sobral ^[2] ; João P,Gomes ^[2] ; Susana,Esteves ^[3] ; Joana,Mendonça ^[4] ; Luis,Vieira ^[4] ; Luís,Martins ^[5] ; Mario,Cunha ^[5] ; Pedro,Montalvão ^[6] ; Miguel,Magalhães ^[6] ; Rui M,Gil da Costa ^[7] ; Ana,Félix ^[8]

作者单位： Research Department, NOVA Medical School University, Lisbon, Portugal, dcochicho@ipolisboa.min-saude.pt.;Virology Laboratory from Clinical Pathology Department, IPOLFG Portuguese Oncology Institute Francisco Gentil, Lisbon, Portugal, dcochicho@ipolisboa.min-saude.pt. ^[1] Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health, Lisbon, Portugal. ^[2] Clinical Research Unit, IPOLFG Portuguese Oncology Institute Francisco Gentil, Lisbon, Portugal. ^[3] Technology and Innovation Unit, Department of Human Genetics, National Institute of Health, Lisbon, Portugal. ^[4] Virology Laboratory from Clinical Pathology Department, IPOLFG Portuguese Oncology Institute Francisco Gentil, Lisbon, Portugal. ^[5] Otorhinolaryngology Department, IPOLFG Portuguese Oncology Institute Francisco Gentil, Lisbon, Portugal. ^[6] LEPABE, Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr Roberto Frias, Porto, Portugal.;ALiCE - Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, Porto, Portugal.;Post-graduate Programme in Adult Health (PPGSAD), University Hospital (HUUFMA) and Morphology Department, Federal University of Maranhão, São Luís, Brazil.;Molecular Oncology and Viral Pathology Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center (Porto.CCC), Porto, Portugal. ^[7] Research Department, NOVA Medical School University, Lisbon, Portugal.;Pathology Department, IPOLFG Portuguese Oncology Institute Francisco Gentil, Lisbon, Portugal. ^[8]

关键词 Head and neck squamous cell carcinoma Human papillomavirus type 16 Human papillomavirus variants Oropharynx Whole-genome sequencing