首页> Cytotherapy> Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.

Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.

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第一作者： Rabea J,Madel

第一单位： Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; Department of Infectious Diseases, West German Centre for Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

作者： Rabea J,Madel ^[1] ; Verena,Börger ^[2] ; Robin,Dittrich ^[2] ; Michel,Bremer ^[2] ; Tobias,Tertel ^[2] ; Nhi Ngo Thi,Phuong ^[3] ; Hideo A,Baba ^[4] ; Lambros,Kordelas ^[5] ; Simon,Staubach ^[2] ; Frank,Stein ^[6] ; Per,Haberkant ^[6] ; Matthias,Hackl ^[7] ; Regina,Grillari ^[8] ; Johannes,Grillari ^[9] ; Jan,Buer ^[3] ; Peter A,Horn ^[2] ; Astrid M,Westendorf ^[3] ; Sven,Brandau ^[10] ; Carsten J,Kirschning ^[11] ; Bernd,Giebel ^[12]

作者单位： Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; Department of Infectious Diseases, West German Centre for Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[1] Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[2] Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[3] Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[4] Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[5] Proteomics Core Facility, EMBL Heidelberg, Heidelberg, Germany. ^[6] TAmiRNA GMBH, Vienna, Austria. ^[7] Evercyte GmbH, Vienna, Austria. ^[8] Evercyte GmbH, Vienna, Austria; University of Natural Resources and Life Science, Vienna, Austria. ^[9] Department of Otorhinolaryngology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[10] Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. Electronic address: carsten.kirschning@uk-essen.de. ^[11] Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. Electronic address: bernd.giebel@uk-essen.de. ^[12]

关键词 exosomes extracellular vesicles graft-versus-host disease heterogeneity mesenchymal stem cells mesenchymal stromal cells

医学主题词人类(Humans);动物(Animals);小鼠(Mice);培养基, 条件性(Culture Media, Conditioned);微RNAs(MicroRNAs);移植物抗宿主病(Graft vs Host Disease);间质干细胞(Mesenchymal Stem Cells)

DOI 10.1016/j.jcyt.2023.03.008

PMID 37055321

发布时间 2024-01-05

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