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Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma.

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作者: Chunmei,Kuang [1] ; Meijuan,Xia [2] ; Gang,An [3] ; CuiCui,Liu [3] ; Cong,Hu [3] ; Jingyu,Zhang [1] ; Zhenhao,Liu [2] ; Bin,Meng [1] ; Pei,Su [2] ; Jiliang,Xia [1] ; Jiaojiao,Guo [2] ; Yinghong,Zhu [1] ; Xing,Liu [2] ; Xuan,Wu [3] ; Yi,Shen [1] ; Xiangling,Feng [2] ; Yanjuan,He [1] ; Jian,Li [2] ; Lugui,Qiu [1] ; Jiaxi,Zhou [2] ; Wen,Zhou [1]
作者单位: Haihe Laboratory of Cell Ecosystem, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Geriatric Disorders, Key Laboratory for Carcinogenesis and Invasion, Chinese Ministry of Education, Key Laboratory of Carcinogenesis, Chinese Ministry of Health, Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China. [1] Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China. [2] State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. [3] Department of Orthopaedic Surgery, Second Xiangya Hospital, Central South University, Changsha, Hunan, China. [4] Xiangya School of Public Health, Central South University, Changsha, Hunan, China. [5] Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [6] State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. zhoujx@ihcams.ac.cn. [7] Haihe Laboratory of Cell Ecosystem, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Geriatric Disorders, Key Laboratory for Carcinogenesis and Invasion, Chinese Ministry of Education, Key Laboratory of Carcinogenesis, Chinese Ministry of Health, Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China. wenzhou@csu.edu.cn. [8] Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China. wenzhou@csu.edu.cn. [9]
DOI 10.1038/s41467-023-37699-z
PMID 37055385
发布时间 2023-04-20
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