M1 Microglia-derived Exosomes Promote Activation of Resting Microglia and Amplifies Proangiogenic Effects through Irf1/miR-155-5p/Socs1 Axis in the Retina.

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第一作者： Xi,Chen

第一单位： State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, No.7 Jinsui Road, Tianhe District, Guangzhou, 510060, China.

作者： Xi,Chen ^[1] ; Xiao,Wang ^[2] ; Zedu,Cui ^[3] ; Qian,Luo ^[1] ; Zihua,Jiang ^[2] ; Yuke,Huang ^[3] ; Jingyi,Jiang ^[1] ; Jin,Qiu ^[2] ; Yan,Li ^[3] ; Keming,Yu ^[1] ; Jing,Zhuang ^[2]

作者单位： State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, No.7 Jinsui Road, Tianhe District, Guangzhou, 510060, China. ^[1] Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. ^[2] Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, China. ^[3]

关键词 exosomes inflammation microglia neovascularization retina

主题词外泌体(Exosomes);巨噬细胞(Macrophages);小神经胶质细胞(Microglia);微RNAs(MicroRNAs);视网膜(Retina);细胞因子信号转导蛋白抑制因子(Suppressor of Cytokine Signaling Proteins);干扰素调节因子1(Interferon Regulatory Factor-1)

DOI 10.7150/ijbs.79784

PMID 37063422

发布时间 2023-05-09

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