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Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.

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第一作者： Andriana G,Kotini

第一单位： Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.;Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.;Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, New York.;Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

作者： Andriana G,Kotini ^[1] ; Saul,Carcamo ^[2] ; Nataly,Cruz-Rodriguez ^[1] ; Malgorzata,Olszewska ^[1] ; Tiansu,Wang ^[1] ; Deniz,Demircioglu ^[2] ; Chan-Jung,Chang ^[1] ; Elsa,Bernard ^[3] ; Mark P,Chao ^[4] ; Ravindra,Majeti ^[4] ; Hanzhi,Luo ^[5] ; Michael G,Kharas ^[5] ; Dan,Hasson ^[2] ; Eirini P,Papapetrou ^[1]

作者单位： Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.;Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.;Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, New York.;Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. ^[1] Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.;Bioinformatics for Next-Generation Sequencing Shared Resource Facility, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York. ^[2] Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York. ^[3] Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California.;Cancer Institute, Stanford University School of Medicine, Stanford, California.;Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California. ^[4] Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.;Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, New York.;Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, New York.;Center for Experimental Therapeutics, Memorial Sloan Kettering Cancer Center, New York, New York. ^[5]

医学主题词人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);表型(Phenotype);基因表达谱(Gene Expression Profiling);遗传变异(Genetic Variation)

DOI 10.1158/2643-3230.BCD-22-0167

PMID 37067914

发布时间 2024-07-11

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Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.

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Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.

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