Frequency and mutational spectrum of PIK3CA gene mutations in breast cancer patients: Largest and first report from Lebanon.

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第一作者： Lama N,Hamadeh

第一单位： Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

作者： Lama N,Hamadeh ^[1] ; Lama,Farhat ^[1] ; Lamia,Hilal ^[1] ; Hazem,Assi ^[2] ; Fadi,Nasr ^[3] ; Georges,Chahine ^[3] ; Joseph,Kattan ^[3] ; Fadi,Farhat ^[4] ; Hampig,Kourie ^[3] ; Georges,El Hachem ^[5] ; Marwan,Ghosn ^[3] ; Nagi,El Saghir ^[2] ; Nabil,Chamseddine ^[5] ; Antoine,Finianos ^[1] ; Hady,Ghanem ^[6] ; Ahmad,Younes ^[7] ; Dany Abi,Gerges ^[6] ; Sally,Temraz ^[2] ; Mohammad,Haidar ^[8] ; Therese,Nabhan ^[8] ; Ali,Chamseddine ^[2] ; Arafat,Tfayli ^[2] ; Ghazi,Zaatari ^[1] ; Rami,Mahfouz ^[9]

作者单位： Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon. ^[1] Department of Internal Medicine. American University of Beirut Medical Center, Beirut, Lebanon. ^[2] Department of Hematology and Oncology. Hotel Dieu de France, Beirut, Lebanon. ^[3] Department of Hematology and Oncology, Hammoud General Hospital, Saida, Lebanon. ^[4] Department of Hematology and Oncology, Saint George Hospital, University of Balamand, Beirut, Lebanon. ^[5] Department of Internal Medicine, Division of Hematology-Oncology, Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon. ^[6] Hematology and Oncology Division, Military Hospital, Beirut, Lebanon. ^[7] Hematology and Oncology Division, Mount Lebanon Hospital, Beirut, Lebanon. ^[8] Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address: rm11@aub.edu.lb. ^[9]

关键词 Breast cancer Lebanon Mutation screening PIK3CA

主题词人类(Humans);女(雌)性(Female);乳腺肿瘤(Breast Neoplasms);黎巴嫩(Lebanon);突变(Mutation);I类磷脂酰肌醇3-激酶类(Class I Phosphatidylinositol 3-Kinases)

DOI 10.1016/j.gene.2023.147433

PMID 37068694

发布时间 2023-05-22

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Frequency and mutational spectrum of PIK3CA gene mutations in breast cancer patients: Largest and first report from Lebanon.

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Frequency and mutational spectrum of PIK3CA gene mutations in breast cancer patients: Largest and first report from Lebanon.

Gene

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Gene

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