<i>Syngap1</i> Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction.

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作者： Abdessattar,Khlaifia ^[1] ; Vidya,Jadhav ^[2] ; Marc,Danik ^[1] ; Théo,Badra ^[2] ; Martin H,Berryer ^[2] ; Alexandre,Dionne-Laporte ^[1] ; Bidisha,Chattopadhyaya ^[2] ; Graziella,Di Cristo ^[1] ; Jean-Claude,Lacaille ^[2] ; Jacques L,Michaud ^[2]

作者单位： Department of Neuroscience, Research Group on Neuronal Signaling and Circuits and Center for Interdisciplinary Research on Brain and Learning, University of Montreal, Montreal, Québec H3C 3J7, Canada. ^[1] University Hospital Center (CHU) Sainte-Justine Research Center, Montréal, Québec H3T1C5, Canada. ^[2] Department of Neuroscience, Research Group on Neuronal Signaling and Circuits and Center for Interdisciplinary Research on Brain and Learning, University of Montreal, Montreal, Québec H3C 3J7, Canada jacques.michaud.med@ssss.gouv.qc.ca jean-claude.lacaille@umontreal.ca. ^[3]

关键词 SYNGAP1 excitatory inputs fast-spiking interneurons hippocampus synaptic deficits

主题词人类(Humans);小鼠(Mice);动物(Animals);小鼠, 转基因(Mice, Transgenic);中间神经元(Interneurons);锥体细胞(Pyramidal Cells);海马(Hippocampus);重组, 遗传(Recombination, Genetic);ras GTP酶激活蛋白质类(ras GTPase-Activating Proteins)

DOI 10.1523/ENEURO.0475-22.2023

PMID 37072176

发布时间 2023-05-19

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eNeuro

2023年10卷5期

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<i>Syngap1</i> Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction.

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<i>Syngap1</i> Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction.

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