Regional spreading pattern is associated with clinical phenotype in amyotrophic lateral sclerosis.

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作者： Alessio,Maranzano ^[1] ; Federico,Verde ^[1] ; Eleonora,Colombo ^[2] ; Barbara,Poletti ^[1] ; Alberto,Doretti ^[1] ; Ruggero,Bonetti ^[1] ; Delia,Gagliardi ^[3] ; Megi,Meneri ^[2] ; Luca,Maderna ^[4] ; Stefano,Messina ^[2] ; Stefania,Corti ^[4] ; Claudia,Morelli ^[1] ; Vincenzo,Silani ^[1] ; Nicola,Ticozzi ^[2]

作者单位： Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, 20149, Italy. ^[1] Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, 20122, Italy. ^[2] Neurology Residency Program, Università degli Studi di Milano, Milan, 20122, Italy. ^[3] Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy. ^[4]

关键词 amyotrophic lateral sclerosis (ALS)disease progression motor neuron disease (MND)motor phenotype site of onset somatotopic organization of motor system

主题词人类(Humans);女(雌)性(Female);肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);回顾性研究(Retrospective Studies);运动神经元(Motor Neurons);表型(Phenotype);疾病恶化(Disease Progression)

DOI 10.1093/brain/awad129

PMID 37075222

发布时间 2023-10-05

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