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首页> Science advances> Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer's disease.

Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer's disease.

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第一作者： Lan-Ting,Zhou
第一单位： Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.;School of Basic Medicine, Hubei University of Arts and Science, Xiangyang, Hubei 441053, China.
作者： Lan-Ting,Zhou [1] ; Dan,Liu [2] ; Hui-Cong,Kang [3] ; Lu,Lu [4] ; He-Zhou,Huang [2] ; Wen-Qing,Ai [2] ; Yang,Zhou [2] ; Man-Fei,Deng [2] ; Hao,Li [2] ; Zhi-Qiang,Liu [2] ; Wei-Feng,Zhang [2] ; Ya-Zhuo,Hu [5] ; Zhi-Tao,Han [5] ; Hong-Hong,Zhang [5] ; Jian-Jun,Jia [5] ; Avijite Kumer,Sarkar [4] ; Saldin,Sharaydeh [4] ; Jie,Wang [6] ; Heng-Ye,Man [7] ; Marcel,Schilling [8] ; Lars,Bertram [8] ; Youming,Lu [2] ; Ziyuan,Guo [4] ; Ling-Qiang,Zhu [2]
作者单位： Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.;School of Basic Medicine, Hubei University of Arts and Science, Xiangyang, Hubei 441053, China. [1] Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. [2] Department of Neurology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. [3] Center for Stem Cell and Organoid Medicine (CuSTOM), Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.;Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH 45229, USA. [4] Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatric Disease, Institute of Geriatrics, Chinese PLA General Hospital and Chinese PLA Medical Academy, Beijing, China. [5] State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Resonance in Biological Systems, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, Hubei 430030, China. [6] Department of Biology, Boston University, Boston, MA 02215, USA. [7] Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), University of Lübeck, Lübeck 23562, Germany. [8]
医学主题词 动物(Animals);小鼠(Mice);阿尔茨海默病(Alzheimer Disease);星形细胞(Astrocytes);疾病模型, 动物(Disease Models, Animal);小鼠, 转基因(Mice, Transgenic);微RNAs(MicroRNAs);神经元(Neurons);tau蛋白质类(tau Proteins);人类(Humans)
DOI 10.1126/sciadv.abq7105
PMID 37083538
发布时间 2024-05-07
基金项目
R21 MH132038/MH/NIMH NIH HHS/United States R21 NS122169/NS/NINDS NIH HHS/United States
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