Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL.
作者:
Anne,Largeot [1]
;
Vanessa,Klapp [1]
;
Elodie,Viry [2]
;
Susanne,Gonder [1]
;
Iria,Fernandez Botana [1]
;
Arnaud,Blomme [2]
;
Mohaned,Benzarti [1]
;
Sandrine,Pierson [2]
;
Chloé,Duculty [3]
;
Petra,Marttila [2]
;
Marina,Wierz [4]
;
Ernesto,Gargiulo [1]
;
Giulia,Pagano [1]
;
Ning,An [2]
;
Najla,El Hachem [5]
;
Daniel,Perez Hernandez [1]
;
Supriya,Chakraborty [1]
;
Loïc,Ysebaert [1]
;
Jean-Hugues,François [2]
;
Susan,Cortez Clemente [3]
;
Guy,Berchem [3]
;
Dimitar G,Efremov [6]
;
Gunnar,Dittmar [7]
;
Martyna,Szpakowska [8]
;
Andy,Chevigné [9]
;
Petr V,Nazarov [10]
;
Thomas,Helleday [10]
;
Pierre,Close [11]
;
Johannes,Meiser [7]
;
Basile,Stamatopoulos [6]
;
Laurent,Désaubry [12]
;
Jérôme,Paggetti [13]
;
Etienne,Moussay [13]
作者单位:
Department of Cancer Research, Tumor Stroma Interactions, Luxembourg Institute of Health, Luxembourg, Luxembourg.
[1]
Faculty of Science, Technology and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
[2]
Laboratory of Cancer Signaling, GIGA Stem Cells, University of Liège, Liège, Belgium.
[3]
Department of Cancer Research, Cancer Metabolism Group, Luxembourg Institute of Health, Luxembourg, Luxembourg.
[4]
Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
[5]
Department of Infection and Immunity, Proteomics of Cellular Signaling, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
[6]
Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
[7]
Haematology Department, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France.
[8]
Laboratoire d'hématologie, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.
[9]
Département d'hémato-oncologie, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.
[10]
Luxembourg Institute of Health, Luxembourg, Luxembourg.
[11]
Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg.
[12]
Department of Infection and Immunity, Immuno-Pharmacology and Interactomics, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
[13]
Department of Cancer Research, Multiomics Data Science, Luxembourg Institute of Health, Luxembourg, Luxembourg.
[14]
Department of Oncology and Metabolism, Weston Park Cancer Centre, The Medical School, University of Sheffield, Sheffield, United Kingdom.
[15]
WELBIO Department, WEL Research Institute, Wavre, Belgium.
[16]
Laboratory of Clinical Cell Therapy, ULB-Research Cancer Center, Jules Bordet Institute, Université Libre de Bruxelles, Brussels, Belgium.
[17]
Regenerative Nanomedicine Laboratory (UMR1260), Faculty of Medicine, Fédération de Médecine Translationnelle de Strasbourg, INSERM-University of Strasbourg, Strasbourg, France.
[18]
主题词
人类(Humans);小鼠(Mice);动物(Animals);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);真核细胞起始因子4F(Eukaryotic Initiation Factor-4F);基因, myc(Genes, myc);RNA, 信使(RNA, Messenger)
DOI
10.1182/blood.2022017839
PMID
37084385
发布时间
2024-03-24
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Blood
Blood
3166-3183页
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