首页> Vaccine> Immunization with a small fragment of the Schmallenberg virus nucleoprotein highly conserved across the Orthobunyaviruses of the Simbu serogroup reduces viremia in SBV challenged IFNAR<sup>-/-</sup> mice.

Immunization with a small fragment of the Schmallenberg virus nucleoprotein highly conserved across the Orthobunyaviruses of the Simbu serogroup reduces viremia in SBV challenged IFNAR<sup>-/-</sup> mice.

导出原文传递

翻译打印收藏纠错

第一作者： Gabriel Soares,Guerra

第一单位： Structure and Cell Biology of Viruses Lab, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia 48160, Spain.

作者： Gabriel Soares,Guerra ^[1] ; Diego,Barriales ^[2] ; Gema,Lorenzo ^[3] ; Sandra,Moreno ^[3] ; Juan,Anguita ^[4] ; Alejandro,Brun ^[3] ; Nicola G A,Abrescia ^[5]

作者单位： Structure and Cell Biology of Viruses Lab, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia 48160, Spain. ^[1] Inflammation and Macrophage Plasticity Laboratory, CIC bioGUNE-BRTA, Derio, Spain. ^[2] Animal Health Research Center (INIA-CISA/CSIC), 28130 Valdeolmos, Madrid, Spain. ^[3] Inflammation and Macrophage Plasticity Laboratory, CIC bioGUNE-BRTA, Derio, Spain; Ikerbasque, Basque Foundation for Science, Bilbao, Bizkaia 48015, Spain. ^[4] Structure and Cell Biology of Viruses Lab, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia 48160, Spain; Ikerbasque, Basque Foundation for Science, Bilbao, Bizkaia 48015, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: nabrescia@cicbiogune.es. ^[5]

关键词 Cell-mediate immunity Orthobunyavirus Pan-vaccine Schmallenberg virus Subunit vaccine