PARP Inhibitors for Prostate Cancer: Tangled up in PROfound and PROpel (and TALAPRO-2) Blues.

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第一作者： Nick,Beije

第一单位： The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, Sutton, UK.

作者： Nick,Beije ^[1] ; Wassim,Abida ^[2] ; Emmanuel S,Antonarakis ^[3] ; Elena,Castro ^[4] ; Ronald,de Wit ^[5] ; Karim,Fizazi ^[6] ; Silke,Gillessen ^[7] ; Maha,Hussain ^[8] ; Joaquin,Mateo ^[9] ; Michael J,Morris ^[2] ; David,Olmos ^[4] ; Oliver,Sartor ^[10] ; Adam,Sharp ^[1] ; Christopher J,Sweeney ^[11] ; Johann S,de Bono ^[12]

作者单位： The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, Sutton, UK. ^[1] Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ^[2] Department of Medicine, University of Minnesota, Minneapolis, MN, USA. ^[3] Department of Medical Oncology, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre, Madrid, Spain. ^[4] Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. ^[5] Institut Gustave Roussy, University of Paris-Saclay, Villejuif, France. ^[6] Istituto Oncologico della Svizzera Italiana, Ente Ospedaliero Cantonale Bellinzona, Bellinzona, Switzerland. ^[7] Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA. ^[8] Vall d'Hebron Institute of Oncology, Barcelona, Spain. ^[9] Tulane Cancer Center, Tulane University Medical School, New Orleans, LA, USA. ^[10] South Australian Immunogenomics Cancer Institute, University of Adelaide, Adelaide, Australia. ^[11] The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, Sutton, UK. Electronic address: johann.de-bono@icr.ac.uk. ^[12]

关键词 Androgen receptor signalling inhibitor Castration-resistant prostate cancer Metastatic prostate cancer PARP inhibitor

主题词男(雄)性(Male);人类(Humans);DNA修复(DNA Repair);信号传导(Signal Transduction)

DOI 10.1016/j.eururo.2023.03.038

PMID 37087376

发布时间 2024-03-13

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