Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily.
第一作者:
Marcel,Rak
第一单位:
Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Max-von-Laue-Str. 9, Frankfurt am Main, 60438, Germany; Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Johann Wolfgang Goethe University, Max-von-Laue-Str. 15, Frankfurt am Main, 60438, Germany.
作者:
医学主题词
AMP活化蛋白激酶类(AMP-Activated Protein Kinases);肝(Liver);蛋白质亚型(Protein Isoforms);蛋白激酶抑制剂(Protein Kinase Inhibitors)
DOI
10.1016/j.ejmech.2023.115347
PMID
37094449
发布时间
2024-01-23
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