Extraction, Structural Characterization, and In Vivo Anti-Inflammatory Effect of Alginate from <i>Cystoseira crinita</i> (Desf.) Borry Harvested in the Bulgarian Black Sea.

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作者： Vesela,Kokova ^[1] ; Paolina,Lukova ^[2] ; Alexandra,Baldzhieva ^[3] ; Plamen,Katsarov ^[4] ; Cédric,Delattre ^[4] ; Roland,Molinié ^[5] ; Emmanuel,Petit ^[6] ; Redouan,Elboutachfaiti ^[7] ; Marianna,Murdjeva ^[8] ; Elisaveta,Apostolova ^[8]

作者单位： Department of Pharmacology, Toxicology, and Pharmacotherapy, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[1] Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria. ^[2] Department of Microbiology and Immunology, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[3] Research Institute at Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[4] Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[5] Clermont Auvergne INP, CNRS, Institut Pascal, Université Clermont Auvergne, 63000 Clermont-Ferrand, France. ^[6] Institut Universitaire de France (IUF), 1 Rue Descartes, 75005 Paris, France. ^[7] UMRT INRAE 1158 BioEcoAgro, BIOlogie des Plantes et Innovation (BIOPI), Avenue des Facultés, IUT d'Amiens, Université de Picardie Jules Verne, Le Bailly, 80025 Amiens, France. ^[8]

关键词 Cystoseira crinita IL-1β Il-6 TNF-α alginate anti-inflammatory effect cytokines histamine peritonitis rat paw edema