Characterizing Biophysical Parameters of Single TCR-pMHC Interactions Using Optical Tweezers.

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第一作者： Hannah M,Stephens

第一单位： Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.

作者： Hannah M,Stephens ^[1] ; Evan,Kirkpatrick ^[1] ; Robert J,Mallis ^[2] ; Ellis L,Reinherz ^[3] ; Matthew J,Lang ^[4]

作者单位： Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. ^[1] Laboratory of Immunobiology and Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Dermatology, Harvard Medical School, Boston, MA, USA. ^[2] Laboratory of Immunobiology and Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA, USA. ^[3] Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. matt.lang@vanderbilt.edu.;Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA. matt.lang@vanderbilt.edu. ^[4]

关键词 Catch bond Mechanosensor Optical tweezers Single molecule T cell T-cell activation T-cell receptor

主题词光镊技术(Optical Tweezers);T淋巴细胞(T-Lymphocytes);受体, 抗原, T细胞, α-β(Receptors, Antigen, T-Cell, alpha-beta);抗原(Antigens);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);蛋白质结合(Protein Binding)

DOI 10.1007/978-1-0716-3135-5_24

PMID 37106195

发布时间 2025-01-04

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准确一般字义偏差语意偏离译文作用小提交