Cardiovascular Toxicities Associated with Anaplastic Lymphoma Kinase Inhibitors: A Disproportionality Analysis of the WHO Pharmacovigilance Database (VigiBase).

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作者： Takahiro,Niimura ^[1] ; Koji,Miyata ^[2] ; Hirofumi,Hamano ^[3] ; Yuuki,Nounin ^[4] ; Hiroto,Unten ^[5] ; Masaki,Yoshino ^[3] ; Satoru,Mitsuboshi ^[3] ; Fuka,Aizawa ^[6] ; Kenta,Yagi ^[7] ; Toshihiro,Koyama ^[8] ; Mitsuhiro,Goda ^[3] ; Yasunari,Kanda ^[6] ; Yuki,Izawa-Ishizawa ^[3] ; Yoshito,Zamami ^[4] ; Keisuke,Ishizawa ^[9]

作者单位： Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, 3-18-15 Kuramoto, Tokushima, 770-8503, Japan. niimura@tokushima-u.ac.jp. ^[1] Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan. niimura@tokushima-u.ac.jp. ^[2] Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, 3-18-15 Kuramoto, Tokushima, 770-8503, Japan. ^[3] Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan. ^[4] Department of Pharmacy, Okayama University Hospital, Okayama, Japan. ^[5] Department of Pharmacy, Tokushima University Hospital, Tokushima, Japan. ^[6] Department of Pharmacy, Niigata Prefectural Cancer Center Hospital, Niigata, Japan. ^[7] Department of Pharmacy, Kaetsu Hospital, Niigata, Japan. ^[8] Department of Health Data Science, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan. ^[9] Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Japan. ^[10] Department of General Medicine, Taoka Hospital, Tokushima, Japan. ^[11]

主题词人类(Humans);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);肺肿瘤(Lung Neoplasms);蛋白激酶抑制剂(Protein Kinase Inhibitors);心包炎(Pericarditis);世界卫生组织(World Health Organization)

DOI 10.1007/s40264-023-01300-9

PMID 37106270

发布时间 2023-05-30

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