Synthesis and Evaluation of Novel Nitric Oxide-Donating Ligustrazine Derivatives as Potent Antiplatelet Aggregation Agents.

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作者： Han-Xu,Li ^[1] ; Jian-Hui,Tian ^[1] ; Hua-Yu,Li ^[1] ; Xin,Wan ^[1] ; Yu,Zou ^[1]

作者单位： Institute of Pharmaceutical Process, Hubei Province Key Laboratory of Occupationl Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan 430065, China. ^[1]

关键词 antiplatelet aggregation agents ligustrazine nitric oxide donors structure-activity relationships

主题词血小板聚集抑制剂(Platelet Aggregation Inhibitors);一氧化氮(Nitric Oxide);血小板聚集(Platelet Aggregation);吡嗪类(Pyrazines);构效关系(Structure-Activity Relationship);花生四烯酸(Arachidonic Acid)

DOI 10.3390/molecules28083355

PMID 37110589

发布时间 2023-05-01

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Molecules (Basel, Switzerland)

2023年28卷8期

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Synthesis and Evaluation of Novel Nitric Oxide-Donating Ligustrazine Derivatives as Potent Antiplatelet Aggregation Agents.

Molecules (Basel, Switzerland)

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Molecules (Basel, Switzerland)

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Synthesis and Evaluation of Novel Nitric Oxide-Donating Ligustrazine Derivatives as Potent Antiplatelet Aggregation Agents.

Molecules (Basel, Switzerland)

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Molecules (Basel, Switzerland)

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