首页> Trials> Effects of a peripherally acting µ-opioid receptor antagonist for the prevention of recurrent acute pancreatitis: study protocol for an investigator-initiated, randomized, placebo-controlled, double-blind clinical trial (PAMORA-RAP trial).

Effects of a peripherally acting µ-opioid receptor antagonist for the prevention of recurrent acute pancreatitis: study protocol for an investigator-initiated, randomized, placebo-controlled, double-blind clinical trial (PAMORA-RAP trial).

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第一作者： Mathias E,Cook

第一单位： Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. m.cook@rn.dk.;Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. m.cook@rn.dk.

作者： Mathias E,Cook ^[1] ; Cecilie S,Knoph ^[2] ; Camilla A,Fjelsted ^[2] ; Jens B,Frøkjær ^[3] ; Anders E,Bilgrau ^[4] ; Srdan,Novovic ^[5] ; Maiken Thyregod,Jørgensen ^[6] ; Michael B,Mortensen ^[6] ; Liv B J,Nielsen ^[7] ; Amer,Hadi ^[7] ; Mark,Berner-Hansen ^[7] ; Wiktor,Rutkowski ^[8] ; Miroslav,Vujasinovic ^[8] ; Matthias,Löhr ^[8] ; Asbjørn M,Drewes ^[2] ; Søren S,Olesen ^[9]

作者单位： Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. m.cook@rn.dk.;Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. m.cook@rn.dk. ^[1] Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.;Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. ^[2] Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.;Department of Radiology, Aalborg University Hospital, Aalborg, Denmark. ^[3] Department of Mathematical Sciences, Aalborg University, Aalborg, Denmark. ^[4] Copenhagen University Hospital Hvidovre, Hvidovre, Denmark. ^[5] Department of Surgery, Odense Pancreas Centre (OPAC), HPB Section, Odense University Hospital, Odense, Denmark. ^[6] Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. ^[7] Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden. ^[8] Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. soso@rn.dk.;Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. soso@rn.dk. ^[9]

关键词 Magnetic resonance imaging Naldemedine Opioid Peripherally acting μ-opioid receptor antagonist Randomized controlled trial Recurrent acute pancreatitis