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Identification of New Compounds against PRRSV Infection by Directly Targeting CD163.

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第一作者： Jiaqi,Zhu

第一单位： Department of Animal Science, Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut, USA.

作者： Jiaqi,Zhu ^[1] ; Xin,He ^[2] ; Denzil,Bernard ^[3] ; Jianing,Shen ^[1] ; Yue,Su ^[1] ; Andrew,Wolek ^[1] ; Brianna,Issacs ^[1] ; Neha,Mishra ^[4] ; Xiuchun,Tian ^[1] ; Antonio,Garmendia ^[4] ; Young,Tang ^[5]

作者单位： Department of Animal Science, Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut, USA. ^[1] Shaanxi Centre of Stem Cells Engineering & Technology, Key Laboratory of Livestock Biology, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. ^[2] Atomwise Inc., San Francisco, California, USA. ^[3] Department of Pathobiology and Veterinary Sciences, University of Connecticut, Storrs, Connecticut, USA. ^[4] Department of Animal Science, Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut, USA.;Shaanxi Centre of Stem Cells Engineering & Technology, Key Laboratory of Livestock Biology, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. ^[5]

关键词 CD163 PRRSV SRCR5 antiviral treatment small molecule compound

医学主题词猪(Swine);动物(Animals);猪呼吸与生殖综合征病毒(Porcine respiratory and reproductive syndrome virus);猪繁殖和呼吸综合征(Porcine Reproductive and Respiratory Syndrome);抗原, 分化, 髓单核细胞(Antigens, Differentiation, Myelomonocytic);受体, 清道夫(Receptors, Scavenger)

DOI 10.1128/jvi.00054-23

PMID 37133376

发布时间 2025-01-03

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