Long-term effectiveness and safety of anti-TNF in pediatric-onset inflammatory bowel diseases: A population-based study.

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作者： Mathurin,Fumery ^[1] ; Claire,Dupont ^[2] ; Delphine,Ley ^[3] ; Guillaume,Savoye ^[4] ; Valérie,Bertrand ^[5] ; Nathalie,Guillon ^[6] ; Pauline,Wils ^[7] ; Corinne,Gower-Rousseau ^[8] ; Helene,Sarter ^[9] ; Dominique,Turck ^[3] ; Ariane,Leroyer ^[9]

作者单位： Amiens University Hospital, Gastroenterology, Amiens, France. Electronic address: fumery.mathurin@chu-amiens.fr. ^[1] Caen University hospital, Pediatrics, Gastroenterology, France. ^[2] CHU Lille, Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Lille, France; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000 Lille, France. ^[3] Rouen University Hospital, Gastroenterology, Rouen, France. ^[4] Le Havre Hospital, Pediatrics, Le Havre, France. ^[5] Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000 Lille, France; Reims University Hospital, Gastroenterology, Reims, France. ^[6] Lille University Hospital, Gastroenterology, EPIMAD registry, Regional house of clinical research, F-59000 Lille, France. ^[7] Reims University Hospital, Gastroenterology, Reims, France. ^[8] Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000 Lille, France; Lille Hospital and University, Public Health, Epidemiology and Economic Health, France. ^[9]

关键词 Crohn's disease Loss of response Primary non-response Ulcerative colitis anti-TNF