首页> BMC cancer> PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair.

PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair.

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第一作者： Fathima,Hameed J S

第一单位： Rajiv Gandhi Centre for Biotechnology, Cancer Research Program, Thycaud, Poojappura, Thiruvananthapuram, Kerala, 695014, India.;Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

作者： Fathima,Hameed J S ^[1] ; Anjali,Devarajan ^[2] ; Devu Priya,M S ^[2] ; Ahel,Bhattacharyya ^[2] ; Mayur Balkrishna,Shirude ^[3] ; Debasree,Dutta ^[4] ; Parimal,Karmakar ^[5] ; Ananda,Mukherjee ^[6]

作者单位： Rajiv Gandhi Centre for Biotechnology, Cancer Research Program, Thycaud, Poojappura, Thiruvananthapuram, Kerala, 695014, India.;Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India. ^[1] Rajiv Gandhi Centre for Biotechnology, Cancer Research Program, Thycaud, Poojappura, Thiruvananthapuram, Kerala, 695014, India. ^[2] Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.;Rajiv Gandhi Centre for Biotechnology, Regenerative Biology Program, Thycaud, Poojappura, Thiruvananthapuram, Kerala, 695014, India. ^[3] Rajiv Gandhi Centre for Biotechnology, Regenerative Biology Program, Thycaud, Poojappura, Thiruvananthapuram, Kerala, 695014, India. ^[4] Department of Life Science and Biotechnology, Jadavpur University, 188, Raja S.C. Mullick Road, Kolkata, West Bengal, 700 032, India. ^[5] Rajiv Gandhi Centre for Biotechnology, Cancer Research Program, Thycaud, Poojappura, Thiruvananthapuram, Kerala, 695014, India. ananda@rgcb.res.in. ^[6]

关键词 DDB2 DNA damage response Endometrial cancer Nucleotide excision repair PTEN RNA polymerase II Unscheduled DNA synthesis