Efficacy of primary series AZD1222 (ChAdOx1 nCoV-19) vaccination against SARS-CoV-2 variants of concern: Final analysis of a randomized, placebo-controlled, phase 1b/2 study in South African adults (COV005).
作者:
Anthonet L,Koen [1]
;
Alane,Izu [1]
;
Vicky,Baillie [1]
;
Gaurav,Kwatra [2]
;
Clare L,Cutland [3]
;
Lee,Fairlie [4]
;
Sherman D,Padayachee [5]
;
Keertan,Dheda [6]
;
Shaun L,Barnabas [7]
;
Qasim Ebrahim,Bhorat [8]
;
Carmen,Briner [9]
;
Khatija,Ahmed [10]
;
Sutika,Bhikha [1]
;
Jinal N,Bhiman [11]
;
Jeanine,du Plessis [1]
;
Aliasgar,Esmail [12]
;
Elizea,Horne [4]
;
Shi-Hsia,Hwa [13]
;
Aylin,Oommen-Jose [1]
;
Teresa,Lambe [14]
;
Matt,Laubscher [1]
;
Mookho,Malahleha [15]
;
Gabriella,Benade [4]
;
Shakeel,McKenzie [1]
;
Suzette,Oelofse [12]
;
Faeezah,Patel [4]
;
Sureshnee,Pillay [16]
;
Sarah,Rhead [17]
;
Hylton,Rodel [13]
;
Carol,Taoushanis [1]
;
Houriiyah,Tegally [16]
;
Asha,Thombrayil [1]
;
Tonya L,Villafana [18]
;
Sarah,Gilbert [19]
;
Andrew J,Pollard [20]
;
Shabir A,Madhi [21]
作者单位:
South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit (Wits-VIDA), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[1]
South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit (Wits-VIDA), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Clinical Microbiology, Christian Medical College, Vellore, India.
[2]
African Leadership in Vaccinology Expertise (ALIVE), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[3]
Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[4]
Setshaba Research Centre, Tshwane, South Africa.
[5]
Centre for Lung Infection and Immunity, Division of Pulmonology, Department of Medicine and UCT Lung Institute, University of Cape Town, South Africa.
[6]
Family Centre for Research with Ubuntu, Department of Paediatrics, Stellenbosch University, Cape Town, South Africa.
[7]
Soweto Clinical Trials Centre, Soweto, South Africa.
[8]
Perinatal HIV Research Unit, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa.
[9]
Setshaba Research Centre, Tshwane, South Africa; Faculty of Health Sciences, Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa.
[10]
National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa; SAMRC Antibody Immunity Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
[11]
Centre for Lung Infection and Immunity, Division of Pulmonology, Department of Medicine and University of Cape Town Lung Institute, Cape Town, South Africa.
[12]
Africa Health Research Institute, Durban, South Africa; Division of Infection and Immunity, University College London, London, UK.
[13]
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, UK; Chinese Academy of Medical Science, Oxford Institute, University of Oxford, Oxford, UK.
[14]
Setshaba Research Centre, Tshwane, South Africa; Synergy Biomed Research Institute, East London, Eastern Cape, South Africa.
[15]
KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa; Centre for Epidemic Response and Innovation (CERI), Stellenbosch University, Stellenbosch, South Africa.
[16]
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, UK.
[17]
Clinical Development, Vaccines & Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
[18]
Nuffield Department of Medicine, University of Oxford, ORCRB, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.
[19]
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.
[20]
South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit (Wits-VIDA), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: shabir.madhi@wits.ac.za.
[21]
DOI
10.1016/j.vaccine.2023.04.058
PMID
37149443
发布时间
2023-05-25
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