Circulating free DNA integrity index and promoter methylation of tumor suppressor gene P16, DAPK and RASSF1A as a biomarker for oropharyngeal squamous cell carcinoma.

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作者： Swati,Kumari ^[1] ; Sridhar,Mishra ^[1] ; Nidhi,Anand ^[1] ; Rahat,Hadi ^[2] ; Madhup,Rastogi ^[2] ; Nuzhat,Husain ^[3]

作者单位： Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomti Nagar, Lucknow, U.P. 226010, India. ^[1] Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomti Nagar, Lucknow, U.P. 226010, India. ^[2] Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomti Nagar, Lucknow, U.P. 226010, India. Electronic address: drnuzhathusain@hotmail.com. ^[3]

关键词 CfDNA integrity Circulating free DNA Liquid biopsy Oropharyngeal cancer Promoter methylation Tumor suppressor genes

主题词人类(Humans);DNA甲基化(DNA Methylation);病例对照研究(Case-Control Studies);头颈部肿瘤(Head and Neck Neoplasms);基因, 肿瘤抑制(Genes, Tumor Suppressor)

DOI 10.1016/j.prp.2023.154489

PMID 37150134

发布时间 2023-05-25

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