Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma.
第一作者:
Jingwei,Cai
第一单位:
Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, 310016, Hangzhou, China.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment 310016, Hangzhou, China.;Zhejiang University Cancer Center, 310058, Hangzhou, China.;Liangzhu Laboratory, Zhejiang University Medical Center, 311121, Hangzhou, China.
作者:
主题词
人类(Humans);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);脂类代谢(Lipid Metabolism);酰基CoA脱氢酶(Acyl-CoA Dehydrogenase);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);细胞系, 肿瘤(Cell Line, Tumor);磷蛋白类(Phosphoproteins);转录因子(Transcription Factors);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic)
DOI
10.7150/ijbs.82177
PMID
37151879
发布时间
2023-05-15
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