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Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus.

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第一作者： Zaid,Taha

第一单位： Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, Canada.;Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.

作者： Zaid,Taha ^[1] ; Mathieu J F,Crupi ^[1] ; Nouf,Alluqmani ^[1] ; Faiha,Fareez ^[2] ; Kristy,Ng ^[3] ; Judy,Sobh ^[3] ; Emily,Lee ^[3] ; Andrew,Chen ^[3] ; Max,Thomson ^[3] ; Marcus M,Spinelli ^[3] ; Carolina S,Ilkow ^[1] ; John C,Bell ^[1] ; Rozanne,Arulanandam ^[3] ; Jean-Simon,Diallo ^[1]

作者单位： Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, Canada.;Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. ^[1] Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. ^[2] Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, Canada. ^[3]

关键词 HER2 Kadcyla?VSVΔ51 antibody-drug conjugate immunotherapy mouse model oncolytic virus trastuzumab

医学主题词人类(Humans);小鼠(Mice);动物(Animals);女(雌)性(Female);乳腺肿瘤(Breast Neoplasms);弹状病毒科(Rhabdoviridae);疾病模型, 动物(Disease Models, Animal)

DOI 10.3389/fimmu.2023.1181014

PMID 37153626

发布时间 2023-05-10

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准确一般字义偏差语意偏离译文作用小提交