Hurdles and signposts on the road to virtual control groups-A case study illustrating the influence of anesthesia protocols on electrolyte levels in rats.

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作者： A,Gurjanov ^[1] ; A,Kreuchwig ^[1] ; T,Steger-Hartmann ^[1] ; L A I,Vaas ^[2]

作者单位： Bayer AG, Pharmaceuticals, Investigational Toxicology, Berlin, Germany. ^[1] Bayer AG, Pharmaceuticals, Research and Pre-Clinical Statistics Group, Berlin, Germany. ^[2]

关键词 3R clinical chemistry historical control data replacement systemic toxicity study virtual control groups

DOI 10.3389/fphar.2023.1142534

PMID 37153793

发布时间 2023-05-09

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Frontiers in pharmacology

2023年14卷

1142534页

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Hurdles and signposts on the road to virtual control groups-A case study illustrating the influence of anesthesia protocols on electrolyte levels in rats.

Frontiers in pharmacology

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Frontiers in pharmacology

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Hurdles and signposts on the road to virtual control groups-A case study illustrating the influence of anesthesia protocols on electrolyte levels in rats.

Frontiers in pharmacology

相似文献

Frontiers in pharmacology

相关期刊

检索历史清除