Expression of S100A8 protein on B cells is associated with disease activity in patients with systemic lupus erythematosus.

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作者： Koji,Kitagori ^[1] ; Takuma,Oku ^[2] ; Masaki,Wakabayashi ^[3] ; Tomoya,Nakajima ^[4] ; Ran,Nakashima ^[1] ; Kosaku,Murakami ^[1] ; Yoshitaka,Hirayama ^[1] ; Yasushi,Ishihama ^[2] ; Koichiro,Ohmura ^[3] ; Akio,Morinobu ^[5] ; Tsuneyo,Mimori ^[6] ; Hajime,Yoshifuji ^[1]

作者单位： Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[1] Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[2] Research Portfolio & Science, Astellas Pharma Inc, Tokyo, Japan. ^[3] Omics Research Center, National Cerebral and Cardiovascular Center, Osaka, Japan. ^[4] Department of Molecular and Cellular Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. ^[5] Kobe City Medical Center General Hospital, Hyogo, Japan. ^[6] Ijinkai Takeda General Hospital, Kyoto, Japan. ^[7] Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. yossii@kuhp.kyoto-u.ac.jp. ^[8]

关键词 B cells S100A8 Systemic lupus erythematosus

主题词人类(Humans);B-淋巴细胞(B-Lymphocytes);钙粒蛋白A(Calgranulin A);红斑狼疮, 系统性(Lupus Erythematosus, Systemic);单核细胞(Monocytes);RNA, 信使(RNA, Messenger)

DOI 10.1186/s13075-023-03057-z

PMID 37165399

发布时间 2023-05-16

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