Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.

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第一作者： Canyu,Liu

第一单位： State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei Province, China.;University of Chinese Academy of Sciences, Beijing, China.

作者： Canyu,Liu ^[1] ; Kaitao,Zhao ^[2] ; Yingshan,Chen ^[1] ; Yongxuan,Yao ^[3] ; Jielin,Tang ^[4] ; Jingjing,Wang ^[2] ; Chonghui,Xu ^[1] ; Qi,Yang ^[4] ; Yi,Zheng ^[1] ; Yifei,Yuan ^[1] ; Hao,Sun ^[1] ; Yongli,Zhang ^[5] ; Yuan,Zhou ^[5] ; Jizheng,Chen ^[6] ; Yun,Wang ^[5] ; Chunchen,Wu ^[7] ; Rongjuan,Pei ^[5] ; Xinwen,Chen ^[8]

作者单位： State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei Province, China.;University of Chinese Academy of Sciences, Beijing, China. ^[1] State Key Laboratory of Virology and Hubei Province Key Laboratory of Allergy and Immunology, Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China. ^[2] Department of Gastroenterology, Guangzhou Women and Children's Medical Center, Guangzhou, China. ^[3] State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei Province, China.;Guangzhou Laboratory, Guangzhou, China. ^[4] State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei Province, China. ^[5] Guangzhou Laboratory, Guangzhou, China. ^[6] Department of Laboratory Medicine, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[7] State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei Province, China.;Guangzhou Laboratory, Guangzhou, China.;Guangzhou Medical University, Guangzhou, China. ^[8]

关键词 GPD2 HBx TRIM28 mitochondria ubiquitin-dependent degradation