Clinical consequences of off-label reduced dosing of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a systematic review and meta-analysis.

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作者： Linda P T,Joosten ^[1] ; Rosanne,van Maanen ^[1] ; Carline J,van den Dries ^[1] ; Frans H,Rutten ^[1] ; Arno W,Hoes ^[1] ; Christopher B,Granger ^[2] ; Martin E W,Hemels ^[3] ; Geert-Jan,Geersing ^[4] ; Sander,van Doorn ^[1]

作者单位： Department of General Practice, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, Netherlands. ^[1] Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA. ^[2] Department of Cardiology, Rijnstate Hospital, Arnhem, Netherlands. ^[3] Department of Cardiology, Radboud University Medical Center, Radboud University, Nijmegen, Netherlands. ^[4] Department of General Practice, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, Netherlands S.vanDoorn@umcutrecht.nl. ^[5]

关键词 Atrial Fibrillation Epidemiology Meta-Analysis Pharmacology, Clinical Systematic Reviews as Topic

主题词人类(Humans);抗凝药(Anticoagulants);心房颤动(Atrial Fibrillation);药品标示外使用(Off-Label Use);投药, 口服(Administration, Oral);卒中(Stroke);出血(Hemorrhage);血栓栓塞(Thromboembolism)

DOI 10.1136/openhrt-2022-002197

PMID 37169490

发布时间 2023-08-11

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2023年10卷1期

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Clinical consequences of off-label reduced dosing of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a systematic review and meta-analysis.

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Clinical consequences of off-label reduced dosing of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a systematic review and meta-analysis.

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