Chemotherapy-induced weight gain in early-stage breast cancer: a prospective matched cohort study reveals associations with inflammation and gut dysbiosis.

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作者： John,Walker ^[1] ; Anil Abraham,Joy ^[2] ; Larissa J,Vos ^[3] ; Trevor H,Stenson ^[4] ; John R,Mackey ^[5] ; Juan,Jovel ^[5] ; Dina,Kao ^[3] ; Karen L,Madsen ^[4] ; Gane Ka-Shu,Wong ^[6]

作者单位： Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, T6G 2H5, Canada. jwwalker@ualberta.ca. ^[1] Division of Medical Oncology, Cross Cancer Institute, Edmonton, AB, T6G 1Z2, Canada. jwwalker@ualberta.ca. ^[2] Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, T6G 2H5, Canada. ^[3] Division of Medical Oncology, Cross Cancer Institute, Edmonton, AB, T6G 1Z2, Canada. ^[4] Clinical Trials Unit, Cross Cancer Institute, Edmonton, AB, T6G 1Z2, Canada. ^[5] The Applied Genomics Core (TAGC), Faculty of Medicine, University of Alberta, Edmonton, AB, T6G 2X8, Canada. ^[6] Division of Gastroenterology, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, T6G 2H5, Canada. ^[7] Department of Biological Sciences, Faculty of Science, University of Alberta, Edmonton, AB, T6G 2E9, Canada. ^[8]

关键词 Adjuvant chemotherapy Dual-energy X-ray absorptiometry Gastrointestinal dysbiosis Inflammatory biomarkers Inflammatory bowel disease Weight gain