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Distinct Profiles of Desensitization of µ-Opioid Receptors Caused by Remifentanil or Fentanyl: In Vitro Assay with Cells and Three-Dimensional Structural Analyses.

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第一作者: Eiko,Uezono
第一单位: Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.;Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
作者单位: Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.;Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan. [1] Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.;Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-0194, Japan. [2] Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.;Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.;Department of Dentistry, National Cancer Center Hospital, Tokyo 104-0045, Japan. [3] Tsumura Research Laboratories, Tsumura and Co., Ibaraki 300-1192, Japan. [4] Department of Anesthesiology and Intensive Care Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan. [5] Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.;Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tokyo 104-0045, Japan. [6] Chemical Biology and In Silico Drug Design, Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan. [7] Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.;Department of Anesthesiology and Pain Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan. [8] Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.;Department of Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan. [9] Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.;Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.;Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.;Department of Pain Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.;Supportive and Palliative Care Research Support Office, National Cancer Center Hospital East, Chiba 277-8577, Japan. [10]
DOI 10.3390/ijms24098369
PMID 37176075
发布时间 2023-05-15
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International journal of molecular sciences

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