Novel CH25H<sup>+</sup> and OASL<sup>+</sup> microglia subclusters play distinct roles in cerebral ischemic stroke.

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作者： Yueman,Zhang ^[1] ; Yunlu,Guo ^[1] ; Ruqi,Li ^[2] ; Tingting,Huang ^[1] ; Yan,Li ^[1] ; Wanqin,Xie ^[1] ; Chen,Chen ^[1] ; Weijie,Chen ^[1] ; Jieqing,Wan ^[2] ; Weifeng,Yu ^[1] ; Peiying,Li ^[3]

作者单位： Department of Anesthesiology, Key Laboratory of the Ministry of Education, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. ^[1] Department of Neurological Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ^[2] Department of Anesthesiology, Key Laboratory of the Ministry of Education, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. peiyingli.md@gmail.com. ^[3] Clinical Research Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. peiyingli.md@gmail.com. ^[4]

关键词 Ischemic stroke Microglia Microglia heterogeneity Neuroprotection Single-cell RNA sequencing

主题词小鼠(Mice);动物(Animals);小神经胶质细胞(Microglia);卒中(Stroke);脑缺血(Brain Ischemia);梗死, 大脑中动脉(Infarction, Middle Cerebral Artery);小鼠, 近交C57BL(Mice, Inbred C57BL)

DOI 10.1186/s12974-023-02799-6

PMID 37183260

发布时间 2023-05-17

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准确一般字义偏差语意偏离译文作用小提交