首页> Cellular and molecular life sciences : CMLS> TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice.

TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice.

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第一作者： Urszula,Doboszewska

第一单位： Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19, 20-033, Lublin, Poland. urszula.doboszewska@uj.edu.pl.;Department of Pharmacobiology, Jagiellonian University Medical College, Medyczna 9, 30-688, Kraków, Poland. urszula.doboszewska@uj.edu.pl.

作者： Urszula,Doboszewska ^[1] ; Katarzyna,Socała ^[2] ; Mateusz,Pieróg ^[2] ; Dorota,Nieoczym ^[2] ; Jan,Sawicki ^[3] ; Małgorzata,Szafarz ^[4] ; Kinga,Gawel ^[5] ; Anna,Rafało-Ulińska ^[6] ; Adam,Sajnóg ^[7] ; Elżbieta,Wyska ^[4] ; Camila V,Esguerra ^[8] ; Bernadeta,Szewczyk ^[6] ; Marzena,Maćkowiak ^[9] ; Danuta,Barałkiewicz ^[7] ; Katarzyna,Mlyniec ^[10] ; Gabriel,Nowak ^[10] ; Ireneusz,Sowa ^[3] ; Piotr,Wlaź ^[2]

作者单位： Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19, 20-033, Lublin, Poland. urszula.doboszewska@uj.edu.pl.;Department of Pharmacobiology, Jagiellonian University Medical College, Medyczna 9, 30-688, Kraków, Poland. urszula.doboszewska@uj.edu.pl. ^[1] Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19, 20-033, Lublin, Poland. ^[2] Department of Analytical Chemistry, Medical University of Lublin, Chodźki 4A, 20-093, Lublin, Poland. ^[3] Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688, Kraków, Poland. ^[4] Department of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego 8B, 20-090, Lublin, Poland. ^[5] Department of Neurobiology, Polish Academy of Sciences, Maj Institute of Pharmacology, Smętna 12, 31-343, Kraków, Poland. ^[6] Department of Trace Analysis, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614, Poznań, Poland. ^[7] Chemical Neuroscience Group, Centre for Molecular Medicine Norway, University of Oslo, Gaustadalléen 21, Forskningsparken, 0349, Oslo, Norway. ^[8] Laboratory of Pharmacology and Brain Biostructure, Department of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343, Kraków, Poland. ^[9] Department of Pharmacobiology, Jagiellonian University Medical College, Medyczna 9, 30-688, Kraków, Poland. ^[10]

关键词 6-Hz seizures BDNF Maximal electroshock seizures TrkB Valproic acid Zinc chloride